Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines
نویسندگان
چکیده
منابع مشابه
Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines.
Multiple myeloma (MM) is an incurable hematological disorder characterized by dysregulated proliferation of terminally differentiated plasma cells. Aberrant histone acetylation has been observed in the development of numerous malignancies. Histone deacetylase inhibitors such as valproic acid (VPA) are promising drugs for cancer therapy since they have been reported to have antiproliferative eff...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2007
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.30.3.573